Medial Temporal Lab, Lund University

Our group’s research centers on neuroimaging in aging and neurodegenerative diseases. Our four areas are:

1. Medial temporal lobe (MTL) subregions are hotspots for neurodegenerative diseases and imaging measures of these regions might therefore be good biomarkers. We focus on two subareas:
   • The development of methods to accurately measure MTL subregions: going from ex vivo validation, to the development of manual segmentation protocols and the incorporation in automated algorithms.
   • The study of imaging measures of MTL subregions to better understand disease mechanisms and improve diagnosis and prognosis of neurodegenerative diseases.
2. Postmortem study of neurodegenerative diseases: As most neurodegenerative pathologies cannot be assessed during life or only imperfectly, postmortem imaging and the study of neurodegenerative pathologies can teach us important lessons.
3. Alzheimer’s disease mimics: There are several groups that present with amnestic syndrome, like Alzheimer’s patients, but have a different etiology. We aim to characterize these patient groups and better understand their etiology and prognosis.